INT326386

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0 Pain Relevance 0

plasma membrane (PROC, Gopc) transport (Gopc) peptidase activity (PROC) extracellular space (PROC) extracellular region (PROC) Golgi apparatus (Gopc)

Anatomy Link Frequency neuronal 1 neural 1 PROC (Homo sapiens) Gopc (Mus musculus)

Pain Link Frequency Relevance Heat cerebral cortex 12 36.00 Thalamus 10 29.28 Hippocampus 22 5.00 cytokine 4 5.00 midbrain 2 5.00 Peripheral nervous system 2 5.00 Neuritis 2 5.00 halothane 2 5.00 Pyramidal cell 2 5.00 interneuron 2 5.00

Disease Link Frequency Relevance Heat Adhesions 32 50.00 Fasciculation 26 5.00 Neuritis 2 5.00 Hypothermia 2 5.00 Cancer 2 5.00 Increased Venous Pressure Under Development 2 5.00 Stroke 2 5.00 Anuria 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Given that NHERF2 has also been found to be highly expressed in neuronal tissue, we also demonstrated interaction of PC with this additional member of the NHERF family (Fig. 2g).

PC Binding (interaction) of Fig in neuronal

1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0

Co-immunoprecipation analyses in brain lysates revealed that neural PC also interacts with RhoA and with the related small GTPase RhoG (Fig. 2h,i).

PC Binding (interacts) of Fig in neural

2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2919383 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.