INT327361

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.33
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Ttr) extracellular space (Ttr) extracellular region (Ttr)
Ttr (Mus musculus)
Ttr - V30M (1)
Pain Link Frequency Relevance Heat
metalloproteinase 10 86.28 High High
Inflammation 18 69.04 Quite High
unmyelinated 2 60.60 Quite High
Spinal cord 2 58.48 Quite High
cytokine 2 49.08 Quite Low
Peripheral nervous system 4 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 22 100.00 Very High Very High Very High
Apoptosis 8 100.00 Very High Very High Very High
Targeted Disruption 16 99.96 Very High Very High Very High
Death 8 87.28 High High
Alzheimer's Dementia 64 87.24 High High
Amyloid Plaque 24 82.44 Quite High
Familial Amyloidotic Polyneuropathy 42 76.08 Quite High
Creutzfeldt Jakob Disease 2 72.32 Quite High
Disease 14 71.36 Quite High
Huntington's Chorea 4 69.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, Tauroursodeoxycholic acid (TUDCA), a biliary acid acting as a potent anti-apoptotic and anti-oxidant was also evaluated in TTR-V30M transgenic mice.
Regulation (evaluated) of TTR-V30M (V30M) associated with targeted disruption and apoptosis
1) Confidence 0.37 Published 2010 Journal J Transl Med Section Body Doc Link PMC2922089 Disease Relevance 1.21 Pain Relevance 0.14
It has been suggested that a possible mechanism for TTR extracellular aggregation is the influence of secreted metabolites generated by oxidative stress and apoptosis on TTR aggregation [12].
Regulation (influence) of TTR associated with stress and apoptosis
2) Confidence 0.37 Published 2010 Journal J Transl Med Section Body Doc Link PMC2922089 Disease Relevance 1.11 Pain Relevance 0.13

General Comments

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