INT327378

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Context Info
Confidence 0.51
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.97
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oxtr) signal transducer activity (Oxtr)
Oxtr (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 92 100.00 Very High Very High Very High
Inflammation 56 99.84 Very High Very High Very High
bradykinin 20 87.04 High High
Dismenorea 12 68.64 Quite High
corticosteroid 8 64.60 Quite High
agonist 36 50.00 Quite Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 60 99.84 Very High Very High Very High
Asthma 136 96.16 Very High Very High Very High
Dysmenorrhea 12 68.64 Quite High
Occupational Lung Diseases 8 51.72 Quite High
Necrosis 12 20.56 Low Low
Cancer 16 20.20 Low Low
Disease 16 5.00 Very Low Very Low Very Low
Injury 8 5.00 Very Low Very Low Very Low
Nicotine Addiction 8 5.00 Very Low Very Low Very Low
Overdose 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The study of the molecular mechanisms regulating the expression of oxytocin receptor remains complex [42,43].
Regulation (regulating) of Gene_expression (expression) of oxytocin receptor
1) Confidence 0.51 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.73 Pain Relevance 0.31
An increased gene transcription was detected by the real time PCR data demonstrating a rapid effect of these cytokines on oxytocin receptor expression.
Regulation (effect) of Gene_expression (expression) of oxytocin receptor associated with cytokine
2) Confidence 0.37 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.28 Pain Relevance 0.24
was more effective in increasing oxytocin receptor expression, oxytocin had no modulating effect on oxytocin-induced calcium responses in HASM cells.
Regulation (effective) of Gene_expression (expression) of oxytocin receptor
3) Confidence 0.37 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.15 Pain Relevance 0.24
These data suggest that expression of oxytocin receptor (OXTR) on HASMCs can be differentially modulated by inflammatory cytokines in HASMCs, a mechanism that may contribute to the altered airway responsiveness observed in asthma assuming that such receptor changes would occur in vivo.
Regulation (modulated) of Gene_expression (expression) of OXTR associated with asthma, inflammation and cytokine
4) Confidence 0.22 Published 2010 Journal Respir Res Section Body Doc Link PMC2922094 Disease Relevance 0.82 Pain Relevance 0.29

General Comments

This test has worked.

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