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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (AQP4, Alms1) transport (AQP4) cilium (Alms1)
lipid metabolic process (Alms1) transmembrane transport (AQP4) plasma membrane (AQP4)
AQP4 (Homo sapiens)
Alms1 (Mus musculus)
Pain Link Frequency Relevance Heat
Demyelination 4 79.36 Quite High
Spinal cord 10 66.08 Quite High
cytokine 2 47.52 Quite Low
Multiple sclerosis 6 43.72 Quite Low
addiction 3 34.52 Quite Low
ischemia 2 32.88 Quite Low
Dopamine 8 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Neuritis 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 57 100.00 Very High Very High Very High
Necrosis 2 92.32 High High
Demyelinating Disease 14 79.36 Quite High
Hyalinosis 1 63.32 Quite High
Hyperplasia 1 62.56 Quite High
Edema 3 40.88 Quite Low
Cv Unclassified Under Development 2 32.88 Quite Low
Disease 69 7.68 Low Low
Motor Neuron Diseases 19 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The limited access of circulating IgG to the extracapillary space in the CNS would only permit interaction of NMO-IgG with AQP4 at the glia limitans of BBB: in consequence of these findings, many authors suggest the perivascular space as the primary target site of the pathogenic process.
AQP4 Binding (interaction) of BBB associated with neuromyelitis optica
1) Confidence 0.03 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923365 Disease Relevance 1.10 Pain Relevance 0.17

General Comments

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