INT327805

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.31
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Rab8a) cytoplasmic membrane-bounded vesicle (Rab8a) plasma membrane (Rab8a)
cytoplasm (Rab8a)
Rab8a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 3 97.16 Very High Very High Very High
Bioavailability 6 94.76 High High
adenocard 36 73.16 Quite High
Glutamate 9 70.72 Quite High
Inflammation 33 55.60 Quite High
Neuropeptide 3 43.08 Quite Low
agonist 6 36.64 Quite Low
Somatosensory cortex 3 15.40 Low Low
cytokine 6 5.48 Low Low
antagonist 15 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 3 97.48 Very High Very High Very High
Sleep Initiation And Maintenance Disorders 6 92.88 High High
Obesity 48 89.44 High High
Appetite Loss 12 83.92 Quite High
Body Weight 6 83.84 Quite High
Sleep Disorders 60 82.48 Quite High
Metabolic Syndrome 129 76.40 Quite High
INFLAMMATION 33 55.60 Quite High
Hyperplasia 9 53.36 Quite High
Injury 6 50.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The simultaneous attenuation of the nocturnal increase in LEP and MEL is reminiscent of that observed in patients with night-eating syndrome [54].
Positive_regulation (increase) of MEL associated with syndrome
1) Confidence 0.07 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923369 Disease Relevance 0.26 Pain Relevance 0
In another study in humans, evening caffeine at a dose corresponding to two ordinary cups of coffee was reported to augment the nocturnal serum MEL levels [41].
Positive_regulation (augment) of MEL
2) Confidence 0.04 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923369 Disease Relevance 0.14 Pain Relevance 0.22
However, when added simultaneously with MEL, LEP release was increased by a robust 250% [44].
Positive_regulation (increased) of MEL
3) Confidence 0.02 Published 2010 Journal Current Neuropharmacology Section Body Doc Link PMC2923369 Disease Relevance 0.92 Pain Relevance 0.08

General Comments

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