INT327976

Context Info Confidence 0.29 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.53 Pain Relevance 0

mitochondrion (BCL2) cell morphogenesis (BCL2) small molecule metabolic process (PNLIP) endoplasmic reticulum (BCL2) intracellular (BCL2) cytoplasm (BCL2)

Anatomy Link Frequency BxPC-3 2 PNLIP (Homo sapiens) BCL2 (Homo sapiens)

Pain Link Frequency Relevance Heat Migraine 1 5.00 rheumatoid arthritis 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 34 94.32 Pancreatic Cancer 21 77.60 Injury 10 57.00 Metastasis 2 43.96 Aggression 2 19.84 Cancer 14 15.28 Death 2 12.64 Parkinson's Disease 2 5.00 Adenocarcinoma 1 5.00 Hepatocellular Cancer 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

PTL obviously decreased the protein expression of antiapoptotic Bcl-2 and increased the protein expression of proapoptotic Bax in the BxPC-3 cells after being treated with indicated concentrations.

PTL Negative_regulation (decreased) of Gene_expression (expression) of Bcl-2 in BxPC-3

1) Confidence 0.29 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2924280 Disease Relevance 0.53 Pain Relevance 0

General Comments

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