INT328187

Context Info Confidence 0.04 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.18

vesicle-mediated transport (Nsf) ATPase activity (Nsf) plasma membrane (Nsf) cytoplasm (Nsf)

Anatomy Link Frequency vesicles 1 Nsf (Rattus norvegicus)

Pain Link Frequency Relevance Heat agonist 36 99.56 Dopamine 46 63.28 Neurotransmitter 7 38.00 Glutamate 9 5.00 Central nervous system 6 5.00 gABA 4 5.00 Paracetamol 1 5.00 Somatostatin 1 5.00 GABAergic 1 5.00

Disease Link Frequency Relevance Heat Schizophrenia 2 21.28 Disease 8 5.00 Death 4 5.00 Neurological Disease 2 5.00 Generalized Anxiety Disorder 2 5.00 Parkinson's Disease 1 5.00 Stress Incontinence 1 5.00 Repression 1 5.00 Apoptosis 1 5.00 Body Weight 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Interestingly, in addition to complexin 1, proteins for both N-ethylmaleimide-sensitive factor (NSF) and soluble NSF attachment protein- (SNAP-) 25, all of which are major players in the exocytosis of neurosecretory vesicles [57], were affected by the D2 agonist.

Regulation (affected) of N-ethylmaleimide-sensitive factor in vesicles associated with agonist

1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924890 Disease Relevance 0 Pain Relevance 0.18

General Comments

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