INT328220

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.52
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp1a) extracellular region (Mmp1a) proteinaceous extracellular matrix (Mmp1a)
Mmp1a (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 33 100.00 Very High Very High Very High
Inflammation 14 99.48 Very High Very High Very High
rheumatoid arthritis 30 54.20 Quite High
metalloproteinase 7 53.92 Quite High
Pain 1 24.16 Low Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 34 100.00 Very High Very High Very High
INFLAMMATION 14 99.48 Very High Very High Very High
Severe Combined Immunodeficiency 14 94.88 High High
Rheumatoid Arthritis 30 54.20 Quite High
Arthralgia 1 24.16 Low Low
Syndrome 1 20.32 Low Low
Disease 5 5.00 Very Low Very Low Very Low
Frailty 2 5.00 Very Low Very Low Very Low
Immunization 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
McolB is apparently devoid of collagenolytic activity.18 Thus, we cannot exclude the possibility that the missing effect of the MMP-13 inhibitor in the AIA model is due to the induction of MMP-1 in a highly inflammatory milieu.
Regulation (effect) of Positive_regulation (induction) of MMP-1 associated with inflammation and arthritis
1) Confidence 0.25 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2925150 Disease Relevance 0.52 Pain Relevance 0.24

General Comments

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