INT328336

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (MCCC2) small molecule metabolic process (MCCC2) cellular nitrogen compound metabolic process (MCCC2)
ligase activity (MCCC2)
Anatomy Link Frequency
fat 1
MCCC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
medulla 4 14.24 Low Low
antagonist 19 5.00 Very Low Very Low Very Low
agonist 17 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Somatostatin 7 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
tolerance 4 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Eae 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 6 96.88 Very High Very High Very High
Hypertrophy 2 86.24 High High
Renal Failure 4 75.00 Quite High
Cancer 6 63.16 Quite High
Body Weight 4 60.40 Quite High
Carcinoma 3 53.00 Quite High
Reprotox - General 1 1 21.12 Low Low
Apoptosis 8 18.96 Low Low
Obesity 15 17.72 Low Low
Targeted Disruption 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Relevant mechanisms embrace repression of insulin-sensitizing genes, such as adiponectin, and induction of adipocyte leptin and peroxisome-proliferating activator receptor- (PPAR-) gamma genes; stimulation of endothelial lipoprotein lipase, adipocyte fatty acid synthase, acetyl CoA carboxylase, and fat-cell glucose uptake; and inhibition of fat oxidation via rate-limiting carnitine-palmitoyl transferase [167, 171, 172, 191, 554, 555].
Positive_regulation (stimulation) of CoA carboxylase in fat associated with repression
1) Confidence 0.02 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.43 Pain Relevance 0

General Comments

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