INT328373

Context Info Confidence 0.05 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.31 Pain Relevance 0.08

extracellular space (Ghrl, GH1) extracellular region (Ghrl, GH1) cytoplasm (Ghrl)

Ghrl (Rattus norvegicus) GH1 (Homo sapiens)

Pain Link Frequency Relevance Heat antagonist 19 94.24 agonist 17 5.00 Inflammation 10 5.00 Somatostatin 7 5.00 medulla 4 5.00 cytokine 4 5.00 tolerance 4 5.00 Neuropeptide 3 5.00 vagus nerve 3 5.00 Eae 3 5.00

Disease Link Frequency Relevance Heat Hyperglycemia 1 91.76 Obesity 15 79.12 Hypertrophy 2 71.44 Hypoglycemia 4 66.40 Osteoporosis 3 35.92 Repression 6 32.08 Apoptosis 8 24.16 Renal Failure 4 13.32 Targeted Disruption 17 5.00 Appetite Loss 13 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

This may be because a significant longterm effect of ghrelin is to drive pulsatile GH secretion, which is strongly lipolytic [4].

Negative_regulation (effect) of ghrelin Positive_regulation (drive) of Localization (secretion) of GH

1) Confidence 0.05 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.31 Pain Relevance 0.08

General Comments

This test has worked.