INT328380

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.55
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (AR, Ghrl) nucleoplasm (AR) transport (AR)
enzyme binding (AR) DNA binding (AR) cell-cell signaling (AR)
AR (Homo sapiens)
Ghrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 1 87.24 High High
addiction 2 56.56 Quite High
Somatostatin 7 33.52 Quite Low
tolerance 4 31.76 Quite Low
antagonist 19 16.88 Low Low
agonist 17 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Neuropeptide 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Polycystic Ovary Syndrome 3 99.74 Very High Very High Very High
Syndrome 3 98.92 Very High Very High Very High
Depression 1 87.24 High High
Renal Failure 4 80.64 Quite High
Thyroid Disease 1 39.20 Quite Low
Weight Gain 3 38.52 Quite Low
Obesity 15 34.92 Quite Low
Impaired Glucose Tolerance 5 31.76 Quite Low
Hyperinsulinism 4 30.64 Quite Low
Targeted Disruption 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The antiandrogen, flutamide, increased ghrelin levels in patients with PCOS, suggesting suppression of ghrelin production via the androgen receptor in this hyperandrogenemic syndrome [152].

2.5.

androgen receptor Negative_regulation (suppression) of Gene_expression (production) of ghrelin associated with syndrome and polycystic ovary syndrome
1) Confidence 0.01 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.55 Pain Relevance 0.07

General Comments

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