INT328999

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Context Info
Confidence 0.16
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (POMC, Mc3r) small molecule metabolic process (POMC) signal transducer activity (Mc3r)
cell-cell signaling (POMC) cytoplasm (POMC) extracellular space (POMC)
POMC (Homo sapiens)
Mc3r (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 1 96.40 Very High Very High Very High
Neuropeptide 35 69.52 Quite High
projection neuron 1 52.00 Quite High
adenocard 1 35.68 Quite Low
Intracerebroventricular 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 5 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Hyperphagia 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-MSH is a peptide derived from the POMC gene and is able to activate the MC3R and MC4R to inhibit food intake and increase energy expenditure [5,23-26].
MSH Positive_regulation (activate) of MC3R
1) Confidence 0.16 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2928777 Disease Relevance 0 Pain Relevance 0.16

General Comments

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