INT329795

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL6, CCL5) aging (IL6, CCL5) extracellular region (IL6, CCL5)
cell-cell signaling (CCL5) cytoplasm (CCL5)
Anatomy Link Frequency
melanocytes 2
IL6 (Homo sapiens)
CCL5 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 24 100.00 Very High Very High Very High
chemokine 6 100.00 Very High Very High Very High
Inflammation 29 80.40 Quite High
psoriasis 19 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
pruritus 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
cryotherapy 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 80.40 Quite High
Disease 14 79.36 Quite High
Cancer 8 78.56 Quite High
Wound Healing 2 77.52 Quite High
Metastasis 2 71.36 Quite High
Sepsis 2 69.92 Quite High
Systemic Lupus Erythematosus 3 67.60 Quite High
Candida Infection 1 30.72 Quite Low
Skin Cancer 29 5.00 Very Low Very Low Very Low
Dermatitis 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When stimulated by TLR ligands, human melanocytes can: (1) release IL-6 and IL-8 cytokines, (2) enhance chemokine (CCL2, CCL3, and CCL5) mRNA production, (3) upregulate phosphorylated I?
IL-6 Positive_regulation (enhance) of Transcription (production) of CCL5 in melanocytes associated with chemokine and cytokine
1) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2933899 Disease Relevance 0.59 Pain Relevance 0.17

General Comments

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