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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.71
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (HHEX) cell proliferation (HHEX) signal transduction (HHEX)
nucleus (HHEX) cell cycle (HHEX) transcription factor binding (HHEX)
HHEX (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 21 99.68 Very High Very High Very High
Pain 16 83.16 Quite High
IPN 3 67.80 Quite High
Opioid 3 66.28 Quite High
Neuropathic pain 2 64.16 Quite High
Inflammation 12 63.32 Quite High
Spinal cord 4 60.48 Quite High
Dorsal horn 2 59.84 Quite High
cytokine 42 46.48 Quite Low
Chronic pancreatitis 1 23.20 Low Low
Disease Link Frequency Relevance Heat
Disease 34 99.96 Very High Very High Very High
Lysosome Storage Disease 8 98.52 Very High Very High Very High
Disease Progression 2 96.76 Very High Very High Very High
Lysosomal Storage Diseases 4 92.40 High High
Pain 20 83.16 Quite High
Nociception 2 82.28 Quite High
Cold Sores 367 77.24 Quite High
Diabetes Mellitus 10 69.56 Quite High
Generalized Anxiety Disorder 2 68.40 Quite High
Inflammatory Pain 3 67.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therapy of lysosomal storage disorders with neurological involvement, such as Tay-Sachs (TS) disease, requires active hexosaminidase (Hex) A production in the CNS and an efficient therapeutic approach that can act faster than human disease progression.
Positive_regulation (requires) of Gene_expression (production) of Hex associated with central nervous system, disease, disease progression and lysosome storage disease
1) Confidence 0.11 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 1.71 Pain Relevance 0.62

General Comments

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