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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.95
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (IL10, MAPK14) nucleoplasm (MAPK14) intracellular (IL10)
cytoplasm (MAPK14) cell-cell signaling (IL10) cytosol (MAPK14)
IL10 (Homo sapiens)
MAPK14 (Homo sapiens)
Pain Link Frequency Relevance Heat
IPN 3 99.86 Very High Very High Very High
cytokine 42 95.08 Very High Very High Very High
Inflammation 12 90.76 High High
Dorsal horn 2 89.68 High High
Spinal cord 4 88.40 High High
Neuropathic pain 2 87.92 High High
Opioid 3 86.80 High High
Chronic pancreatitis 1 71.80 Quite High
Pain 16 68.32 Quite High
Enkephalin 6 39.64 Quite Low
Disease Link Frequency Relevance Heat
Cold Sores 367 100.00 Very High Very High Very High
Inflammatory Pain 3 99.86 Very High Very High Very High
Cancer 202 96.28 Very High Very High Very High
Necrosis 2 96.00 Very High Very High Very High
INFLAMMATION 15 90.76 High High
Neuropathic Pain 7 87.92 High High
Generalized Anxiety Disorder 2 84.64 Quite High
Pancreatitis 2 71.80 Quite High
Diabetes Mellitus 10 70.00 Quite High
Pain 20 68.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mata and colleagues have demonstrated, in a rat model of inflammatory pain, that expression of IL-10 by a HSV-1 vector in DRG prevents activation of p38 mitogen-activated protein kynase (p38 MAPK) and expression of full-length membrane-spanning tumour necrosis factor-?
Gene_expression (expression) of IL-10 Negative_regulation (prevents) of Positive_regulation (activation) of p38 associated with necrosis, cold sores, cancer and ipn
1) Confidence 0.00 Published 2010 Journal The Open Virology Journal Section Body Doc Link PMC2936037 Disease Relevance 1.95 Pain Relevance 1.18

General Comments

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