INT330980

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Icam1) cell adhesion (Icam1) plasma membrane (Icam1)
Anatomy Link Frequency
nasal mucosa 2
Icam1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 8 100.00 Very High Very High Very High
Onset of action 3 33.96 Quite Low
Antihistamine 10 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
pruritus 3 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 16 100.00 Very High Very High Very High
Conjunctiva Disease 23 82.56 Quite High
Pressure And Volume Under Development 4 59.52 Quite High
Pruritus 16 59.36 Quite High
Disorders Of The Lacrimal System 5 58.68 Quite High
Conjunctivitis 4 57.80 Quite High
Erythema 1 56.24 Quite High
Hypersensitivity 34 5.00 Very Low Very Low Very Low
Bites And Stings 3 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both subjective (symptom scores) and objective (impression cytology) parameters established the antiallergic activity of azelastine in the eye, and confirmed its inhibitory effect on infiltration of inflammation and downregulation of ICAM-1, which was first observed in the nasal mucosa.14
Regulation (effect) of Negative_regulation (downregulation) of ICAM-1 in nasal mucosa associated with inflammation
1) Confidence 0.21 Published 2010 Journal Clinical Ophthalmology (Auckland, N.Z.) Section Body Doc Link PMC2938280 Disease Relevance 0.68 Pain Relevance 0.09

General Comments

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