INT332331

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Cdk5, Rbm39) embryo development (Cdk5) cytoplasm (Cdk5)
cytosol (Cdk5) nucleocytoplasmic transport (Cdk5) cell death (Cdk5)
Anatomy Link Frequency
neuronal 1
Cdk5 (Mus musculus)
Rbm39 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 18 51.52 Quite High
Migraine 18 50.00 Quite Low
Trigeminal ganglion neurons 5 14.60 Low Low
agonist 10 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
headache 7 5.00 Very Low Very Low Very Low
qutenza 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 19 51.52 Quite High
Ganglion Cysts 11 50.00 Quite Low
Migraine With Aura 5 50.00 Quite Low
Migraine Disorders 13 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Epilepsy 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Headache 3 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The inverse correlation between P2X3 serine phosphorylation and P2X3 activity (i.e., reduced serine phosphorylation associated with enhanced P2X3 receptor function) suggests that P2X3 serine dephosphorylation could be an important molecular contributor to receptor operation, particularly in view of the fact that Cdk5 (a kinase associated with negative P2X3 receptor regulating function [26]) was less associated with P2X3 receptors in neuronal membranes of KI neurons.
Cdk5 Binding (associated) of receptors in neuronal
1) Confidence 0.00 Published 2010 Journal Mol Pain Section Body Doc Link PMC2940876 Disease Relevance 0.05 Pain Relevance 0.05

General Comments

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