INT332933

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PPARG) enzyme binding (PPARG) DNA binding (PPARG)
lipid metabolic process (PPARG) cytoplasm (PPARG) cytosol (PPARG)
PPARG (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 30 5.00 Very Low Very Low Very Low
agonist 12 5.00 Very Low Very Low Very Low
dexamethasone 3 5.00 Very Low Very Low Very Low
cINOD 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 153 98.68 Very High Very High Very High
Diabetes Mellitus 45 94.00 High High
Diabetic Retinopathy 3 93.52 High High
Disease 69 87.88 High High
Insulin Resistance 21 81.20 Quite High
Metabolic Syndrome 9 79.36 Quite High
INFLAMMATION 33 5.00 Very Low Very Low Very Low
Atherosclerosis 12 5.00 Very Low Very Low Very Low
Hyperandrogenism 12 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other three variants in PPARG putative promoter have been identified: A-14G, C-681G, and C-689T [71], even though their impact on PPARG transcription and function has not been completely elucidated.
Regulation (impact) of Transcription (transcription) of PPARG
1) Confidence 0.43 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.53 Pain Relevance 0
Another PPARG nucleotide variation, affecting PPAR?
Regulation (affecting) of Transcription (variation) of PPARG
2) Confidence 0.38 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.53 Pain Relevance 0
It has been hypothesized that this SNP might alter PPARG transcript abundance influencing in turn the expression levels of some PPAR?
Regulation (alter) of Transcription (abundance) of PPARG
3) Confidence 0.38 Published 2010 Journal PPAR Research Section Body Doc Link PMC2943117 Disease Relevance 0.65 Pain Relevance 0

General Comments

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