INT333452

Context Info Confidence 0.18 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

nucleoplasm (ATM, TP53) DNA binding (ATM, TP53) nucleus (ATM, TP53) cytoplasm (ATM, TP53) cell differentiation (TP53) mitochondrion (TP53)

ATM (Homo sapiens) TP53 (Homo sapiens)

Pain Link Frequency Relevance Heat long-term potentiation 7 5.00 nMDA receptor 2 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 7 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

These two relationships are illustrated in Figure 7 where we see ATM activating CHK1, CHK2 and MDM2 inhibiting p53.

ATM Positive_regulation (activating) of Negative_regulation (inhibiting) of p53

1) Confidence 0.18 Published 2010 Journal BMC Bioinformatics Section Body Doc Link PMC2944280 Disease Relevance 0 Pain Relevance 0

General Comments

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