INT334343

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GRP, GRP) extracellular space (GRP, GRP) extracellular region (GRP, GRP)
cell differentiation (Helt) nucleus (Helt) DNA binding (Helt)
Anatomy Link Frequency
GABAergic neurons 4
GRP (Homo sapiens)
GRP (Homo sapiens)
Helt (Mus musculus)
Pain Link Frequency Relevance Heat
GABAergic 32 100.00 Very High Very High Very High
gABA 18 98.76 Very High Very High Very High
Anterior cingulate cortex 96 97.52 Very High Very High Very High
Pyramidal cell 54 96.00 Very High Very High Very High
amygdala 28 89.84 High High
Action potential 18 86.76 High High
Hippocampus 2 67.04 Quite High
antagonist 14 61.68 Quite High
Pain 2 22.08 Low Low
Glutamate 2 17.04 Low Low
Disease Link Frequency Relevance Heat
Pain 4 22.08 Low Low
Cognitive Disorder 2 19.84 Low Low
Pruritus 22 5.00 Very Low Very Low Very Low
Anxiety Disorder 16 5.00 Very Low Very Low Very Low
Drug Dependence 2 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several lines of evidence in the present study suggest that GRP acts on somatodendritic GRP receptor in GABAergic neurons to induce neuronal firing and GABA release in interneurons, thereby decreasing the excitability of pyramidal neurons.
GRP Regulation (acts) of GRP Binding (receptor) of GABAergic in GABAergic neurons associated with gaba, pyramidal cell and gabaergic
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2945970 Disease Relevance 0 Pain Relevance 0.90
Several lines of evidence in the present study suggest that GRP acts on somatodendritic GRP receptor in GABAergic neurons to induce neuronal firing and GABA release in interneurons, thereby decreasing the excitability of pyramidal neurons.
GRP Regulation (acts) of GRP Binding (receptor) of neurons in GABAergic neurons associated with gaba, pyramidal cell and gabaergic
2) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2945970 Disease Relevance 0 Pain Relevance 0.91

General Comments

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