INT334384

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.33
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nptx2)
Nptx2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Bioavailability 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 39 75.00 Quite High
Lung Cancer 3 58.88 Quite High
Injury 3 23.48 Low Low
Toxicity 15 5.00 Very Low Very Low Very Low
Adenocarcinoma 9 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 6 5.00 Very Low Very Low Very Low
Body Weight 3 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low
Hemolysis 3 5.00 Very Low Very Low Very Low
Stroke 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observation that incubation of the mitochondrial fraction with positively charged Si NP-NH2 produced more ROS than incubation with neutral Si NP-N3 and negatively charged Si NP-COOH is in agreement with findings reported by Xia et al.[42].
Gene_expression (produced) of NP-NH2
1) Confidence 0.07 Published 2010 Journal Part Fibre Toxicol Section Body Doc Link PMC2946263 Disease Relevance 0.06 Pain Relevance 0
Upon exposure to Si NP-NH2 intracellular ROS production started at low concentrations and then grew rapidly reaching a plateau at concentrations above 46 ng/ml (EC50 value = 18 ng/ml; Table 2).
Gene_expression (production) of NP-NH2
2) Confidence 0.07 Published 2010 Journal Part Fibre Toxicol Section Body Doc Link PMC2946263 Disease Relevance 0 Pain Relevance 0
Si NP-NH2 produced the highest level of intracellular ROS, followed by Si NP-N3 and Si NP-COOH; the latter did not induce any intracellular ROS production.
Gene_expression (produced) of NP-NH2
3) Confidence 0.07 Published 2010 Journal Part Fibre Toxicol Section Abstract Doc Link PMC2946263 Disease Relevance 0.27 Pain Relevance 0

General Comments

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