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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sox10) extracellular space (C4b) extracellular region (C4b)
nucleus (Sox10) DNA binding (Sox10) transcription factor binding (Sox10)
Anatomy Link Frequency
C4b (Mus musculus)
Sox10 (Mus musculus)
Pain Link Frequency Relevance Heat
unmyelinated 2 60.40 Quite High
nav1.8 1 45.12 Quite Low
c fibre 1 44.56 Quite Low
Peripheral nervous system 2 38.56 Quite Low
Central nervous system 1 33.72 Quite Low
Demyelination 6 27.12 Quite Low
dorsal root ganglion 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Demyelinating Disease 7 27.12 Quite Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Adhesions 2 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, NFAT c4 complexes with Sox-10, a transcription factor required for myelination [17], to activate the promoter and myelin-specific enhancer of the Krox-20 gene, which globally regulates peripheral myelination [11,18-20], and also with the promoter of the myelin protein zero (P0) gene, all of which underline the involvement of NFAT proteins in myelination.
Positive_regulation (activate) of c4 Binding (complexes) of Sox-10 in NFAT
1) Confidence 0.04 Published 2010 Journal F1000 Biol Rep Section Body Doc Link PMC2948355 Disease Relevance 0 Pain Relevance 0.03

General Comments

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