INT335129

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid metabolic process (PPARA, Insig1) lipid binding (PPARA) nucleoplasm (PPARA)
small molecule metabolic process (PPARA) endoplasmic reticulum (Insig1) nucleus (PPARA)
PPARA (Homo sapiens)
Insig1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 30 80.20 Quite High
Inflammatory response 2 46.56 Quite Low
Inflammation 14 5.00 Very Low Very Low Very Low
Bile 9 5.00 Very Low Very Low Very Low
Endocannabinoid 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 2 95.08 Very High Very High Very High
Obesity 14 58.08 Quite High
INFLAMMATION 16 46.20 Quite Low
Disorder Of Lipid Metabolism 14 5.00 Very Low Very Low Very Low
Nash(non-alcoholic Steatohepatitis) 3 5.00 Very Low Very Low Very Low
Fatty Liver 2 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low
Dyslipidemia /

Combined Dyslipidemia

2 5.00 Very Low Very Low Very Low
Hypoglycemia 2 5.00 Very Low Very Low Very Low
Liver Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
activation reduced expression of lipogenic genes, including Fasn, Gpam, and SREBP1c, while Insig1 expression was increased by PPAR?
PPAR Positive_regulation (increased) of Gene_expression (expression) of Insig1
1) Confidence 0.20 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0.15 Pain Relevance 0.07

General Comments

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