INT335495

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Context Info
Confidence 0.21
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.22
Pain Relevance 1.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Aif1) cytoplasm (Aif1)
Anatomy Link Frequency
dorsal 4
ventral 4
lateral 2
Aif1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 177 95.60 Very High Very High Very High
ischemia 244 93.64 High High
Dorsal horn 7 92.92 High High
Spinal cord 9 91.80 High High
fifth nerve 7 75.84 Quite High
primary afferent fibers 1 74.88 Quite High
Snapping jaw 42 73.16 Quite High
Inflammation 48 72.16 Quite High
Sciatic nerve 6 69.00 Quite High
Central nervous system 30 65.08 Quite High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 196 93.64 High High
Temporomandibular Joint Syndrome 42 73.16 Quite High
INFLAMMATION 60 72.16 Quite High
Death 48 50.00 Quite Low
Transient Ischemic Attack 40 50.00 Quite Low
Ganglion Cysts 39 30.00 Quite Low
Respiratory Failure 4 16.88 Low Low
Pain 22 5.00 Very Low Very Low Very Low
Neuropathic Pain 16 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Up-regulation of IBA-1 immunoreactivity was also detected in the dorsal part of Sp5 (blue arrowheads in Figures 1I and 3I) and ventral cochlear nucleus (VC) (red arrowheads in Figures 1I and 4I) in 2 out of 4 animals (50%).
Regulation (regulation) of Regulation (immunoreactivity) of IBA-1 in dorsal
1) Confidence 0.21 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.19 Pain Relevance 0.19
Up-regulation of IBA-1 immunoreactivity was detected in LVe (blue arrows in Figures 1J and 2J) and the ventral part of Sp5 (red arrows in Figures 1J and 3J) in all three animals (100%).
Regulation (regulation) of Regulation (immunoreactivity) of IBA-1 in ventral
2) Confidence 0.21 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.16 Pain Relevance 0.16
Up-regulation of IBA-1 immunoreactivity was also detected in the dorsal part of Sp5 (blue arrowheads in Figures 1J and 3J) and ventral cochlear nucleus (VC) (red arrowheads in Figures 1J and 4J) in one out of three animals (33%).
Regulation (regulation) of Regulation (immunoreactivity) of IBA-1 in dorsal
3) Confidence 0.21 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.15 Pain Relevance 0.15
Up-regulation of IBA-1 immunoreactivity was detected in LVe (blue arrows in Figures 1I and 2I) and the ventral part of Sp5 (red arrows in Figures 1I and 3I) in 3 out of 4 animals (75%).
Regulation (regulation) of Regulation (immunoreactivity) of IBA-1 in ventral
4) Confidence 0.21 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.22 Pain Relevance 0.22
As shown in Figure 5, in saline-injected rats no changes in Iba1 immunoreactivity were observed between the contra- and ipsi-lateral sides of either the trigeminal subnucleus caudalis of the medulla oblongata (p = 0.836; n = 8 animals) (Figure 5A) or of the dorsal horn of the cervical spinal cord (p = 0.918; n = 8 animals) (Figure 5C).
Neg (no) Regulation (changes) of Neg (no) Regulation (immunoreactivity) of Iba1 in lateral associated with medulla, dorsal horn and spinal cord
5) Confidence 0.21 Published 2010 Journal Mol Pain Section Body Doc Link PMC3017032 Disease Relevance 0.50 Pain Relevance 0.79

General Comments

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