INT335497

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Map2) intracellular (Map2) protein complex (Map2)
cytoplasm (Map2)
Map2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 61 98.32 Very High Very High Very High
medulla 41 50.00 Quite Low
Glutamate receptor 1 43.08 Quite Low
cytokine 1 10.80 Low Low
anesthesia 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Hippocampus 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 49 98.32 Very High Very High Very High
Death 12 85.76 High High
Apoptosis 1 78.20 Quite High
Injury 2 58.80 Quite High
Transient Ischemic Attack 10 50.00 Quite Low
Cv General 4 Under Development 2 12.28 Low Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ischemia-induced rapid elevation of intracellular Ca2+ concentration and subsequent activation of Ca2+-dependent phosphatases (e.g., calcineurin) and proteases (e.g., calpains) can lead to dephosphorylation and proteolytic degradation of MAP2 [18,19].
Positive_regulation (lead) of Protein_catabolism (degradation) of MAP2 associated with ischemia
1) Confidence 0.32 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2949765 Disease Relevance 0.61 Pain Relevance 0.16

General Comments

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