INT335525

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (SGCB, SPHK1) small molecule metabolic process (SPHK1) DNA binding (SPHK1)
cytosol (SPHK1) protein folding (SPHK1) signal transduction (SPHK1)
SGCB (Homo sapiens)
SPHK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Carcinoma 182 100.00 Very High Very High Very High
Cancer 84 87.76 High High
Apoptosis 6 65.84 Quite High
Disease 14 5.00 Very Low Very Low Very Low
Adenoid Cystic Carcinoma 10 5.00 Very Low Very Low Very Low
Metastasis 8 5.00 Very Low Very Low Very Low
Mucoepidermoid Carcinoma 8 5.00 Very Low Very Low Very Low
Recurrence 6 5.00 Very Low Very Low Very Low
Skin Cancer 4 5.00 Very Low Very Low Very Low
Reprotox - General 1 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SPHK1 expression is associated with the prognosis of patients with SGC
SGC Binding (associated) of SPHK1 associated with carcinoma
1) Confidence 0.22 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2949806 Disease Relevance 0.55 Pain Relevance 0
Our data showed that the upregulation of SPHK1 mRNA and protein is a universal and frequent event in human SGC tissues, which indicates that SPHK1 overexpression might be associated with the development and progression of SGC.
SGC Spec (might) Binding (associated) of SPHK1 associated with carcinoma
2) Confidence 0.21 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2949806 Disease Relevance 1.06 Pain Relevance 0

General Comments

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