INT335725

Context Info Confidence 0.55 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.99 Pain Relevance 0

lipid binding (Vcp) cytosol (Vcp) transport (Vcp) endoplasmic reticulum (Vcp) ATPase activity (Vcp) nucleus (Vcp)

Vcp (Mus musculus)

Pain Link Frequency Relevance Heat Eae 5 43.16 Hippocampus 4 5.00 imagery 3 5.00 cytokine 2 5.00 anesthesia 1 5.00 isoflurane 1 5.00 Neurotransmitter 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Apoptosis 24 99.60 Convulsion 13 80.60 Disease 27 78.16 Lifespan 1 77.64 Targeted Disruption 95 72.88 Muscle Weakness 17 71.12 Brain Disease 3 61.20 Muscle Disease 10 50.00 Cognitive Disorder 6 43.16 Dementia 3 31.88

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The finding that inhibition of VCP expression promotes apoptosis [44] suggests that intact VCP is indispensable for normal development and cell survival.

Negative_regulation (inhibition) of Gene_expression (expression) of VCP associated with apoptosis

1) Confidence 0.55 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2950155 Disease Relevance 0.99 Pain Relevance 0

General Comments

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