INT336665

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (P2rx1, P2rx2) protein complex (P2rx1)
P2rx1 (Rattus norvegicus)
P2rx2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 1 99.72 Very High Very High Very High
antagonist 7 96.52 Very High Very High Very High
sodium channel 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
agonist 4 5.00 Very Low Very Low Very Low
ASIC 3 5.00 Very Low Very Low Very Low
Neuropathic pain 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Thrombosis 1 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Hypercalcemia 1 5.00 Very Low Very Low Very Low
Syndrome 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Suramin and its analogue NF449 appear to owe much of their high potency at the human P2X1 receptor (compared with that of the rat) to an interaction with Lys138 (Asp136 in rat P2X2) [31].
P2X1 Binding (interaction) of P2X2 associated with potency
1) Confidence 0.07 Published 2010 Journal Trends in Pharmacological Sciences Section Body Doc Link PMC2954318 Disease Relevance 0 Pain Relevance 0.14

General Comments

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