INT337082

Context Info Confidence 0.68 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.97 Pain Relevance 0

isomerase activity (Mif) cell proliferation (Mif) extracellular space (Mif) extracellular region (Mif) nucleus (Mif) cytoplasm (Mif)

Mif (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 20 50.00 cytokine 8 42.68 Inflammatory response 2 5.00 dexamethasone 1 5.00 cINOD 1 5.00 fibrosis 1 5.00 chemokine 1 5.00 rheumatoid arthritis 1 5.00 cva 1 5.00

Disease Link Frequency Relevance Heat Cancer 41 99.92 Hyperplasia 1 89.36 Death 4 85.72 Colon Cancer 4 82.28 Intestinal Cancer 1 76.04 Disease 10 72.92 Malignant Neoplastic Disease 2 57.24 Reprotox - General 1 3 55.04 INFLAMMATION 23 50.00 Breast Cancer 4 49.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The importance of this activity is clear when you consider that this is the main outcome of mutations in Ras which occur in a third of human tumours.28 MIF stimulates phosphorylation of p42/p44 MAPK through PKA.

Phosphorylation (phosphorylation) of MIF associated with cancer

1) Confidence 0.68 Published 2010 Journal QJM: An International Journal of Medicine Section Body Doc Link PMC2955282 Disease Relevance 0.97 Pain Relevance 0

General Comments

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