INT337111

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Mapk1) mitochondrion (Mapk1) protein complex (Mapk1)
cytoplasm (Mapk1) cytosol (Mapk1) signal transduction (Mapk1)
Anatomy Link Frequency
neurons 3
Nr1d2-rs2 (Mus musculus)
Mapk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 21 100.00 Very High Very High Very High
antagonist 2 99.72 Very High Very High Very High
Nucleus accumbens 9 81.52 Quite High
cocaine 5 65.40 Quite High
Enkephalin 5 5.00 Very Low Very Low Very Low
substance P 5 5.00 Very Low Very Low Very Low
GABAergic 4 5.00 Very Low Very Low Very Low
Dynorphin 3 5.00 Very Low Very Low Very Low
projection neuron 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 93.28 High High
Stress 1 59.44 Quite High
Cognitive Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of D2R antagonists suggest that stimulation of D2Rs by basal or psychostimulant-induced DA release prevents the activation of ERK signaling events in neurons containing these receptors.
Positive_regulation (stimulation) of D2Rs in neurons Negative_regulation (prevents) of Positive_regulation (activation) of ERK in neurons associated with dopamine and antagonist
1) Confidence 0.00 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2955397 Disease Relevance 0.15 Pain Relevance 0.31

General Comments

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