INT337379

Context Info Confidence 0.16 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.30 Pain Relevance 0.10

mitochondrion (GK2) carbohydrate metabolic process (GK2) cytoplasm (GK2)

GK2 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammatory response 2 97.88 aspirin 2 5.00 cytokine 2 5.00 cINOD 2 5.00 Inflammation 2 5.00 alcohol 2 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 6 97.52 Stress 54 51.84 Hypoxia 20 5.00 Disease 14 5.00 Aging 12 5.00 Apoptosis 12 5.00 Cardiovascular Disease 10 5.00 Nicotine Addiction 8 5.00 Diabetes Mellitus 4 5.00 Coronary Artery Disease 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Two of the downregulated gene transcripts, hormone-sensitive lipase (LIPE) and glycerol kinase 2 (GK2), are targets for the nuclear receptor, peroxisome proliferator-activated receptor-?

Regulation (sensitive) of Localization (lipase) of glycerol kinase 2

1) Confidence 0.16 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.15 Pain Relevance 0.05

Two of the downregulated gene transcripts, hormone-sensitive lipase (LIPE) and glycerol kinase 2 (GK2), are targets for the nuclear receptor, peroxisome proliferator-activated receptor-?

Regulation (sensitive) of Localization (lipase) of GK2

2) Confidence 0.16 Published 2010 Journal BMC Med Section Body Doc Link PMC2955589 Disease Relevance 0.15 Pain Relevance 0.05

General Comments

This test has worked.