INT338021

Context Info Confidence 0.14 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.33 Pain Relevance 0

cytoplasm (Flna, AR) nucleus (Flna, AR) transcription factor binding (Flna, AR) nucleoplasm (AR) transport (AR) enzyme binding (AR)

Anatomy Link Frequency hinge 3 Flna (Mus musculus) AR (Homo sapiens)

Pain Link Frequency Relevance Heat member 8 2 5.00 monoamine 2 5.00 opioid receptor 2 5.00 agonist 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Reprotox - General 1 94 82.48 Death 7 48.72 Metastasis 5 35.88 Cancer 14 25.40 Disease 6 5.00 Apoptosis 4 5.00 Recurrence 4 5.00 Shock 2 5.00 Myelodysplastic Syndromes 2 5.00 Retinoblastoma 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A fragment of the protein product of FLNA negatively regulates transcription by AR through a physical interaction with the hinge region [110].

FLNA Binding (interaction) of in hinge Regulation (regulates) of Transcription (transcription) of AR in hinge

1) Confidence 0.14 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2956710 Disease Relevance 0.33 Pain Relevance 0

General Comments

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