INT338997

Context Info Confidence 0.10 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.35 Pain Relevance 0.08

Anatomy Link Frequency osteoblasts 1 BTF3P11 (Homo sapiens)

Pain Link Frequency Relevance Heat dexamethasone 5 98.88 Potency 2 70.56 Inflammation 7 39.84 abdominal pain 1 39.44 cytokine 4 5.00 Parenteral administration 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Osteoporosis 36 95.20 Hypercalcemia 1 66.20 Spontaneous Fractures 1 54.20 Injury 30 50.00 Aging 8 50.00 Aseptic Necrosis Of Bone 1 46.16 Ulcers 1 42.72 INFLAMMATION 7 39.84 Abdominal Pain 1 39.44 Vomiting 1 38.80

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

OPG is a soluble decoy RANK receptor, secreted by osteoblasts, that binds surface RANK ligand (RANKL) on osteoblasts.

Localization (secreted) of OPG in osteoblasts

1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2958849 Disease Relevance 0.35 Pain Relevance 0.08

General Comments

This test has worked.