INT339070

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 2 Disease Relevance 3.81 Pain Relevance 0.61

cell adhesion (Mog)

Mog (Rattus norvegicus) Eae1 (Mus musculus)

Pain Link Frequency Relevance Heat Multiple sclerosis 52 97.76 Inflammation 66 93.52 Demyelination 6 92.96 Spinal cord 60 68.00 agonist 8 39.64 Central nervous system 20 5.00 COX2 12 5.00 cytokine 6 5.00 Inflammatory mediators 4 5.00 depression 2 5.00

Disease Link Frequency Relevance Heat Multiple Sclerosis 264 100.00 Stress 154 99.04 INFLAMMATION 72 93.52 Demyelinating Disease 10 92.96 Disease 46 92.60 Recurrence 10 87.08 Urological Neuroanatomy 20 5.00 Central Nervous System Disease 18 5.00 Paralysis 12 5.00 Immunization 4 5.00

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Dark Agouti rats were inoculated with MOG/CFA to induce EAE, and an immobilisation stress protocol with two different durations (12 and 21 days, starting at the moment of MOG-inoculation) was applied in order to analyse the effect of stress on disease onset and neuroinflammation.

MOG Positive_regulation (induce) of EAE associated with stress, multiple sclerosis and disease

1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Abstract Doc Link PMC2958904 Disease Relevance 1.99 Pain Relevance 0.30

Chronic immobilisation stress ameliorates clinical score and neuroinflammation in a MOG-induced EAE in Dark Agouti rats: mechanisms implicated Background

MOG Positive_regulation (induced) of EAE associated with stress and multiple sclerosis

2) Confidence 0.00 Published 2010 Journal J Neuroinflammation Section Title Doc Link PMC2958904 Disease Relevance 1.83 Pain Relevance 0.31

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