INT339583

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.38
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ABCA1, RPE) isomerase activity (RPE) transport (ABCA1)
Golgi apparatus (ABCA1) intracellular (ABCA1) carbohydrate metabolic process (RPE)
ABCA1 (Homo sapiens)
RPE (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 90.08 High High
Spinal cord 1 25.84 Quite Low
Central nervous system 1 13.84 Low Low
adenocard 3 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
interneuron 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 56 99.48 Very High Very High Very High
Ocular Toxicity (including Many Sub-types) 14 97.48 Very High Very High Very High
Age-related Macular Degeneration 64 95.52 Very High Very High Very High
Stress 4 91.36 High High
INFLAMMATION 3 90.08 High High
Retinal Diseases 11 89.56 High High
Obesity 1 73.68 Quite High
Nicotine Addiction 2 72.60 Quite High
Aging 4 65.36 Quite High
Frailty 4 26.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This contributes to disease pathogenesis by cleaving RPE cell attachment to Bruch's membrane, which causes disruption of membrane transport and subsequent RPE demise [25].
membrane Binding (attachment) of RPE associated with disease
1) Confidence 0.03 Published 2009 Journal Stem Cells (Dayton, Ohio) Section Body Doc Link PMC2962903 Disease Relevance 1.38 Pain Relevance 0.05

General Comments

This test has worked.

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