INT340377

Context Info Confidence 0.35 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.82 Pain Relevance 0

endosome (Clcn4-2, Clcn5) transport (Clcn4-2, Clcn5) transmembrane transport (Clcn4-2, Clcn5) Golgi apparatus (Clcn5) plasma membrane (Clcn5)

Clcn4-2 (Mus musculus) Clcn5 (Mus musculus)

Pain Link Frequency Relevance Heat Sicca syndrome 1 5.00 fibrosis 1 5.00 Glutamate 1 5.00 Pain 1 5.00 medulla 1 5.00 abdominal pain 1 5.00

Disease Link Frequency Relevance Heat Dent Disease 19 92.16 Disease 50 87.12 Cerebellooculorenal Syndrome 12 80.96 Cataract 7 48.04 Nephrocalcinosis 14 34.56 Kidney Stones 41 33.72 Congenital Anomalies 3 13.48 Proteinuria 16 5.00 Rickets 10 5.00 Phosphate Metabolism Disorders 8 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

ClC-4 and cofilin) that interact with ClC-5 [18] has been investigated but no mutations in CLCN4 or COFILIN were identified [8].

ClC-4 Binding (interact) of ClC-5

1) Confidence 0.35 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2964617 Disease Relevance 0.82 Pain Relevance 0

General Comments

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