INT341042

Context Info Confidence 0.34 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0

aging (Aqp2) plasma membrane (Aqp2) protein complex (Aqp2) transmembrane transport (Aqp2) lysosome (Aqp2) cytoplasm (Aqp2)

Anatomy Link Frequency urine 2 Aqp2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat antagonist 4 5.00 withdrawal 3 5.00 alcohol 2 5.00 cINOD 1 5.00 depression 1 5.00 Calcium channel 1 5.00

Disease Link Frequency Relevance Heat Renal Disease 10 66.16 Diabetes Insipidus 3 39.44 Polyuria 1 35.52 Chronic Renal Failure 13 34.40 Water Intoxication 1 27.76 Disease 7 5.00 Pressure And Volume Under Development 6 5.00 Obesity 5 5.00 Renal Insufficiency 3 5.00 Body Weight 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The concentration of AQP2 was not significantly changed during the urine concentrating test in Groups 3 and 4, but increased significantly in the other two groups.

Neg (not) Positive_regulation (increased) of Protein_catabolism (concentration) of AQP2 in urine

1) Confidence 0.34 Published 2010 Journal BMC Nephrol Section Body Doc Link PMC2965705 Disease Relevance 0.07 Pain Relevance 0

General Comments

This test has worked.