INT342130

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.16
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (ACE2) extracellular space (ACE2) extracellular region (ACE2)
plasma membrane (ACE2)
ACE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 18 99.28 Very High Very High Very High
Osteoarthritis 50 98.24 Very High Very High Very High
corticosteroid 1 87.96 High High
Pain 31 84.76 Quite High
cytokine 7 71.08 Quite High
Pain score 12 45.72 Quite Low
cINOD 5 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 20 99.28 Very High Very High Very High
Osteoarthritis 50 98.24 Very High Very High Very High
Pressure And Volume Under Development 1 85.28 High High
Pain 42 84.76 Quite High
Synovitis 1 81.12 Quite High
Adhesions 5 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Arthritis 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In this study to find out possible mechanism of actions of Aflapin we carried out in vitro studies to evaluate whether Aflapin can inhibit metalloprotease secretion or influence the inflammatory component of osteoarthritis.
Negative_regulation (inhibit) of Localization (secretion) of metalloprotease associated with inflammation and osteoarthritis
1) Confidence 0.01 Published 2010 Journal International Journal of Medical Sciences Section Body Doc Link PMC2974165 Disease Relevance 1.16 Pain Relevance 0.74

General Comments

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