INT342153

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

extracellular region (MUC7, Gast) signal transduction (Gast)

MUC7 (Homo sapiens) Gast (Rattus norvegicus)

Pain Link Frequency Relevance Heat Somatostatin 14 5.00 Calcitonin gene-related peptide 13 5.00 agonist 7 5.00 dorsal root ganglion 2 5.00 Cholecystokinin 2 5.00 ASIC 2 5.00 Neuropeptide 2 5.00 nud 2 5.00 antagonist 2 5.00 Central nervous system 1 5.00

Disease Link Frequency Relevance Heat Ganglion Cysts 4 5.00 Ulcers 2 5.00 Targeted Disruption 2 5.00 Dyspepsia 2 5.00 Loss Of Sense Of Smell 2 5.00 Nociception 2 5.00 Increased Venous Pressure Under Development 2 5.00 Acid Reflux 1 5.00 Gastritis 1 5.00 Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In clinical studies, high pH, tryptic peptides, and luminal divalent metals (Ca2+ and Mg2+) increase gastrin release and acid production.

Mg2 Positive_regulation (increase) of Localization (release) of gastrin

1) Confidence 0.01 Published 2010 Journal Curr Gastroenterol Rep Section Abstract Doc Link PMC2974196 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.