INT342599

Context Info Confidence 0.32 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.99 Pain Relevance 0.20

nucleus (Fos, Jun) DNA binding (Fos, Jun) transcription factor binding (Fos, Jun) cytosol (Jun)

Anatomy Link Frequency cardiomyocyte 1 Fos (Mus musculus) Jun (Mus musculus)

Pain Link Frequency Relevance Heat Inflammation 7 76.40 cytokine 2 73.60 ischemia 6 57.96 Central nervous system 2 43.48 withdrawal 2 40.20 Morphine 3 39.76 narcan 4 34.48 alcohol 3 5.00 Arthritis 3 5.00 fibrosis 2 5.00

Disease Link Frequency Relevance Heat Coronary Heart Disease 32 99.64 Disease 9 85.92 INFLAMMATION 7 76.40 Apoptosis 6 60.48 Cv Unclassified Under Development 3 57.96 Coronary Artery Disease 3 55.32 Injury 2 17.60 Hypoxia 2 16.96 Death 3 16.24 Cerebral Hypoxia 1 6.84

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Results indicated that the expression of c-fos increased in cardiomyocyte of VMC mice, and that c-Fos can compose AP-1 with c-jun gene products.

Fos Binding (compose) of AP-1 in cardiomyocyte associated with coronary heart disease

1) Confidence 0.32 Published 2010 Journal Virol J Section Body Doc Link PMC2976746 Disease Relevance 0.99 Pain Relevance 0.20

General Comments

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