INT342989

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL8, SFTPA1) extracellular region (IL8, SFTPA1) signal transduction (IL8)
intracellular (IL8)
IL8 (Homo sapiens)
SFTPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 27 100.00 Very High Very High Very High
chemokine 9 99.48 Very High Very High Very High
antagonist 18 98.96 Very High Very High Very High
calcitonin gene related peptide 16 91.24 High High
Inflammatory mediators 14 88.56 High High
Inflammation 37 56.00 Quite High
cytokine 9 36.32 Quite Low
qutenza 6 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
TRP channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 48 88.16 High High
Hyperplasia 1 54.48 Quite High
Gastroesophageal Reflux Disease 12 52.44 Quite High
Injury 5 38.84 Quite Low
Acid Reflux 3 24.40 Low Low
Esophageal Disease 22 23.48 Low Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Ileitis 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, a selective IL-8 antibody, a PAF receptor antagonist, and an neurokinin-1 receptor antagonist (ie, SP antagonist) significantly reduced PBL migration, supporting a role of IL-8, PAF and SP as relevant chemokines.
IL-8 Regulation (role) of SP associated with chemokine, antagonist and substance p
1) Confidence 0.02 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 0.38 Pain Relevance 0.60

General Comments

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