INT344314

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.67
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK8) mitochondrion (MAPK8) cell morphogenesis (PDPN)
embryo development (PDPN) response to stress (MAPK8) cytoplasm (MAPK8)
PDPN (Homo sapiens)
MAPK8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 3 89.04 High High
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 246 90.72 High High
Skin Cancer 51 69.72 Quite High
Lung Cancer 3 51.80 Quite High
Adenocarcinoma 3 50.64 Quite High
Malignant Neoplastic Disease 42 44.08 Quite Low
Metastasis 75 37.76 Quite Low
Breast Cancer 3 33.56 Quite Low
Small Cell Lung Carcinoma 6 5.00 Very Low Very Low Very Low
Germ Cell And Embryonal Neoplasms 3 5.00 Very Low Very Low Very Low
Respiratory Failure 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A decreased level of phosphorylated JNK but not of total JNK was induced by siRNA-mediated podoplanin knockdown (Figures 6D and 7C), suggesting that podoplanin could induce JNK phosphorylation.
podoplanin Positive_regulation (induce) of Phosphorylation (phosphorylation) of JNK
1) Confidence 0.35 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.15 Pain Relevance 0.04
A decreased level of phosphorylated JNK but not of total JNK was induced by siRNA-mediated podoplanin knockdown (Figures 6D and 7C), suggesting that podoplanin could induce JNK phosphorylation.
podoplanin Positive_regulation (induce) of Phosphorylation (phosphorylation) of JNK
2) Confidence 0.35 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.26 Pain Relevance 0.04
A decreased level of phosphorylated JNK but not of total JNK was induced by siRNA-mediated podoplanin knockdown (Figures 6D and 7C), suggesting that podoplanin could induce JNK phosphorylation.
podoplanin Positive_regulation (induce) of Phosphorylation (phosphorylated) of JNK
3) Confidence 0.35 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.26 Pain Relevance 0.04

General Comments

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