INT346411

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.17 Pain Relevance 0.14

cell differentiation (Caprin1) mitochondrion (Mtus1) Golgi apparatus (Mtus1) cytoplasm (Caprin1) RNA binding (Caprin1) plasma membrane (Mtus1)

Anatomy Link Frequency spinal cord neurons 1 Caprin1 (Mus musculus) Mtus1 (Mus musculus)

Pain Link Frequency Relevance Heat Spinal cord 46 96.40 Central nervous system 6 82.28 tetrodotoxin 14 5.00 Action potential 5 5.00 Neurotransmitter 4 5.00 antagonist 3 5.00 sodium channel 1 5.00 nMDA receptor antagonist 1 5.00 gABA 1 5.00 Glutamate 1 5.00

Disease Link Frequency Relevance Heat Pheochromocytoma 1 94.76 Paralysis 7 73.88 Anaerobic Bacterial Infections 22 50.00 Targeted Disruption 6 5.00 Disease 6 5.00 Infection 4 5.00 Poisoning 2 5.00 Injury 2 5.00 Toxicity 1 5.00 Death 1 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, the receptor-binding domain of TeNT was reported to bind to a GPI-anchored protein that was sensitive to phosphoinositol specific phosholipase C (PI-PLC) treatment in MNs, spinal cord neurons, and PC12 cells (rat pheochromocytoma cell line).

GPI-anchored protein Binding (bind) of receptor-binding in spinal cord neurons associated with pheochromocytoma and spinal cord

1) Confidence 0.00 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2991259 Disease Relevance 0.17 Pain Relevance 0.14

General Comments

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