INT346578

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.22
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Sh3gl3) endosome (Sh3gl3) cytoplasm (Sh3gl3)
Anatomy Link Frequency
brain 1
urine 1
Sh3gl3 (Mus musculus)
Pain Link Frequency Relevance Heat
peripheral neuropathy 6 18.72 Low Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Peripheral nervous system 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
analgesia 2 5.00 Very Low Very Low Very Low
hypoalgesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 62.16 Quite High
Fabry Disease 36 53.68 Quite High
Renal Failure 2 52.76 Quite High
Renal Insufficiency 2 45.84 Quite Low
Polyuria 2 39.16 Quite Low
Proteinuria 2 37.60 Quite Low
Neuropathic Pain 6 37.44 Quite Low
Death 2 36.80 Quite Low
Chronic Renal Failure 2 35.56 Quite Low
Renal Disease 2 34.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One exception was the brain, where no difference was seen between treated and untreated mice, though the increase of GL-3 in both treated and untreated Fabry mice was significant (p<0.0001) relative to the wild-type control.
Localization (increase) of GL-3 in brain
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0 Pain Relevance 0
Figure 2C depicts the total GL-3 excreted over 24 h, showing that although SRT significantly decreased urine GL-3 (?
Localization (excreted) of GL-3 in urine
2) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2991350 Disease Relevance 0.22 Pain Relevance 0

General Comments

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