INT347057

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Context Info
Confidence 0.58
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.05
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gnat2) GTPase activity (Gnat2) signal transducer activity (Gnat2)
Gnat2 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 18 82.76 Quite High
Glutamate receptor 6 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retina Disease 9 52.88 Quite High
Targeted Disruption 15 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low
Camurati-engelmann Disease 6 5.00 Very Low Very Low Very Low
Sunburn 6 5.00 Very Low Very Low Very Low
Aids-related Complex 3 5.00 Very Low Very Low Very Low
Bites And Stings 3 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Reflex Sympathetic Dystrophy 3 5.00 Very Low Very Low Very Low
Mydriatic 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The observation that mice carrying a cytotoxin (DTA) under control of the Gnat2 promoter display aggressive rod degeneration [29]provides indirect support for the concept of Gnat2 expression in rods, as this does not occur with other cone-specific promoters[30].
Gene_expression (expression) of Gnat2
1) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993945 Disease Relevance 0 Pain Relevance 0.03
Nevertheless, if Gnat2 really is present in all rods this begs the question of why Calvert et al. (2000) found most Gnat1?
Gene_expression (present) of Gnat2
2) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993945 Disease Relevance 0.05 Pain Relevance 0
Our immunocytochemical evidence for low-level Gnat2 expression in rods provides support for this possibility.
Gene_expression (expression) of Gnat2
3) Confidence 0.50 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2993945 Disease Relevance 0 Pain Relevance 0.11

General Comments

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