INT347639

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.97 Pain Relevance 0.14

cytosol (Hdac4) nucleus (Hdac4) DNA binding (Hdac4) transcription factor binding (Hdac4) cytoplasm (Hdac4)

Atp9a (Mus musculus) Hdac4 (Mus musculus)

Pain Link Frequency Relevance Heat fibrosis 6 96.96 Analgesic 1 5.00 Potency 1 5.00 Bioavailability 1 5.00

Disease Link Frequency Relevance Heat Fibrosis 6 96.96 Stomach Cancer 36 85.96 Aggression 2 85.24 Metastasis 2 79.04 Adhesions 1 67.80 Malignant Neoplastic Disease 1 60.64 Cancer 22 55.12 Apoptosis 26 50.00 Epilepsy 3 5.00 Adenocarcinoma 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, VPA can also inhibit an activity of HDAC4 which is one of class II HDACs [29].

class II Binding (activity) of HDAC4

1) Confidence 0.01 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2994814 Disease Relevance 0.97 Pain Relevance 0.14

General Comments

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