INT348040

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, Tlr2) plasma membrane (TNF, Tlr2) intracellular (TNF, Tlr2)
extracellular space (TNF) extracellular region (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
hepatocytes 2
TNF (Homo sapiens)
Tlr2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 23 97.16 Very High Very High Very High
cytokine 10 62.24 Quite High
alcohol 1 54.00 Quite High
fibrosis 4 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 23 97.16 Very High Very High Very High
Hepatocellular Cancer 47 84.12 Quite High
Liver Cancer 3 81.20 Quite High
Cancer 40 80.16 Quite High
Disease 1 78.72 Quite High
Nash(non-alcoholic Steatohepatitis) 9 72.72 Quite High
Obesity 3 67.92 Quite High
Alcoholic Liver Diseases 2 64.20 Quite High
Injury 4 43.36 Quite Low
Hepatitis C Virus Infection 8 35.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TLR2 expression in hepatocytes is upregulated by LPS, TNF, and others, suggesting that hepatocytes become more sensitive in the inflammatory condition [92].
TNF Positive_regulation (upregulated) of Gene_expression (expression) of TLR2 in hepatocytes associated with inflammation
1) Confidence 0.02 Published 2010 Journal Gastroenterology Research and Practice Section Body Doc Link PMC2995932 Disease Relevance 0.98 Pain Relevance 0.14

General Comments

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