INT349659

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (PYCARD, ADRB2) endosome (ADRB2) intracellular (PYCARD)
signal transducer activity (ADRB2) cytosol (PYCARD) signal transduction (PYCARD)
PYCARD (Homo sapiens)
ADRB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 40 92.48 High High
Potency 5 82.24 Quite High
Inflammation 3 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
beta blocker 2 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 19 96.88 Very High Very High Very High
Pulmonary Disease 11 96.44 Very High Very High Very High
Disease 6 5.00 Very Low Very Low Very Low
Airway Obstruction 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Heart Rate Under Development 3 5.00 Very Low Very Low Very Low
INFLAMMATION 3 5.00 Very Low Very Low Very Low
Stroke 3 5.00 Very Low Very Low Very Low
Anxiety 2 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These observations suggest that the B2AR activity can be enhanced allosterically by Asc through a novel mechanism that may provide means to improve the treatment of asthma and COPD.
Asc Positive_regulation (enhanced) of B2AR associated with asthma and pulmonary disease
1) Confidence 0.06 Published 2010 Journal PLoS ONE Section Body Doc Link PMC3001466 Disease Relevance 0.19 Pain Relevance 0.17

General Comments

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