INT34969

From wiki-pain
Revision as of 12:04, 22 September 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1983
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.55
Pain Relevance 2.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Ptgs1) aging (Ptgs1) Golgi apparatus (Ptgs1)
endoplasmic reticulum (Ptgs1) cytoplasm (Ptgs1) lipid binding (Ptgs1)
Anatomy Link Frequency
knee joints 2
dorsal horn 2
Ptgs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
acular 8 100.00 Very High Very High Very High
Inflammation 42 99.74 Very High Very High Very High
substance P 11 99.08 Very High Very High Very High
aspirin 2 98.84 Very High Very High Very High
Calcitonin gene-related peptide 7 98.56 Very High Very High Very High
dorsal root ganglion 107 97.44 Very High Very High Very High
Dynorphin 4 97.08 Very High Very High Very High
Dorsal horn 7 96.40 Very High Very High Very High
Hyperalgesia 10 95.04 Very High Very High Very High
Sciatic nerve 2 92.76 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 107 97.44 Very High Very High Very High
Nervous System Injury 3 95.40 Very High Very High Very High
Hyperalgesia 11 95.04 Very High Very High Very High
INFLAMMATION 39 94.76 High High
Pressure And Volume Under Development 2 91.84 High High
Neuropathic Pain 3 86.04 High High
Arthritis 30 84.04 Quite High
Nociception 2 69.44 Quite High
Pain 11 50.00 Quite Low
Arthralgia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
When administered perorally, indomethacin inhibited cyclooxygenase product formation, phenidone inhibited 5-lipoxygenase product formation, and 3-amino-1-(m-[trifluoromethyl]-phenyl)-2-pyrazoline (BW 755C) inhibited formation of products of both pathways.
Negative_regulation (inhibited) of cyclooxygenase Binding (formation) of
1) Confidence 0.37 Published 1987 Journal Biochem. Pharmacol. Section Abstract Doc Link 3103625 Disease Relevance 0.60 Pain Relevance 0.53
Intraplantar injection of a cyclooxygenase inhibitor ketorolac reduces immunoreactivities of substance P, calcitonin gene-related peptide, and dynorphin in the dorsal horn of rats with nerve injury or inflammation.
Negative_regulation (reduces) of cyclooxygenase Binding (injection) of in dorsal horn associated with nervous system injury, inflammation, dynorphin, dorsal horn, acular, calcitonin gene-related peptide and substance p
2) Confidence 0.10 Published 2003 Journal Neuroscience Section Title Doc Link 14568028 Disease Relevance 0.49 Pain Relevance 1.36
Furthermore, co-cultures of DRG neurones and FLS cells from normal or acutely and chronically inflamed knee joints were made in a medium containing either the cyclooxygenase (COX) inhibitor indomethacin (1 ?
Negative_regulation (inhibitor) of cyclooxygenase Binding (indomethacin) of in knee joints associated with dorsal root ganglion
3) Confidence 0.05 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1860064 Disease Relevance 0.46 Pain Relevance 0.44
Arachidonic acid-dependent binding of ANFT and benzidine by prostaglandin endoperoxide synthetase was inhibited by anaerobic conditions and aspirin.
Negative_regulation (inhibited) of prostaglandin endoperoxide synthetase Binding (binding) of associated with aspirin
4) Confidence 0.03 Published 1983 Journal Cancer Res. Section Abstract Doc Link 6403225 Disease Relevance 0 Pain Relevance 0.23

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox