INT350096

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.32 Pain Relevance 0.20

endoplasmic reticulum (Hmox1) enzyme binding (Hmox1) signal transducer activity (Hmox1) cytosol (Hmox1) signal transduction (Hmox1) cell death (Hmox1)

Hmox1 (Mus musculus) MRXS5 (Homo sapiens)

Pain Link Frequency Relevance Heat Pain 1 82.12 Inflammation 21 81.76 Inflammatory response 2 79.76 cytokine 3 10.32 COX-2 inhibitor 2 5.00 Inflammatory mediators 1 5.00

Disease Link Frequency Relevance Heat Pain 1 82.12 INFLAMMATION 19 81.76 Vasculitis 4 25.60 Bacterial Infection 6 22.80 Injury 6 17.04 Stress 7 5.00 Infection 3 5.00 Apoptosis 2 5.00 Sepsis 2 5.00 Adenovirus Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Some studies also demonstrated an inhibitory effect of HO-1 on PGs production.

HO-1 Negative_regulation (effect) of Gene_expression (production) of PGs

1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC3002338 Disease Relevance 0.32 Pain Relevance 0.20

General Comments

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